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Antibody Product Overview
| ELK.No | ES4135 |
| Product name | CD294 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC;IF;ELISA |
| Other name | PTGDR2; CRTH2; DL1R; GPR44; Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD294 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 11251 |
| Human Swiss-Prot | Q9Y5Y4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CD294 |
| Fields | |
| Gene name | PTGDR2 |
| Protein name | Prostaglandin D2 receptor 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14764 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z2J6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 309212 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6XKD3 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2. AA range:161-210 |
| Specificity | CD294 Polyclonal Antibody detects endogenous levels of CD294 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 43kD |
| Background | This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011], |
| Function | function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . Internalized receptors colocalized with RAB11A. . |
| Expression | Widespread expression. High expression in stomach, small intestine, heart and thymus. Intermediate expression in colon, spinal cord and peripheral blood and low expression in brain, skeletal muscle and spleen. Expressed also on Th2- and Tc2- type cells, eosinophils and basophils. |
Additional Images
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Western Blot analysis of 293 cells using CD294 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
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Western blot analysis of lysate from 293 cells, using PTGDR2 Antibody.
: AO-06-ES4135-50
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