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Antibody Product Overview
| ELK.No | ES4142 |
| Product name | Nov rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC;IF;ELISA |
| Other name | NOV; CCN3; IGFBP9; NOVH; Protein NOV homolog; NovH; CCN family member 3; Insulin-like growth factor-binding protein 9; IBP-9; IGF-binding protein 9; IGFBP-9; Nephroblastoma-overexpressed gene protein homolog |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4856 |
| Human Swiss-Prot | P48745 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Nov |
| Fields | |
| Gene name | NOV |
| Protein name | Protein NOV homolog |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18133 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q64299 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 81526 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9QZQ5 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human NOV. AA range:221-270 |
| Specificity | Nov Polyclonal Antibody detects endogenous levels of Nov protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 39kD |
| Background | The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009], |
| Function | function:Immediate-early protein likely to play a role in cell growth regulation.,similarity:Belongs to the CCN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 TSP type-1 domain.,similarity:Contains 1 VWFC domain.,subunit:Interacts with FBLN1.,tissue specificity:Increased expression in Wilms tumor of the stromal type., |
| Subcellular location | Secreted. Cytoplasm . Cell junction, gap junction . Localizes at the gap junction in presence of GJA1. . |
| Expression | Expressed in endiothelial cells (at protein level) (PubMed:21063504). Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type. |
Additional Images
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Western Blot analysis of MCF-7 cells using Nov Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100
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Western blot analysis of lysate from MCF-7 cells, using NOV Antibody.
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: AO-06-ES4142-50
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