CD300f rabbit pAb

CD300f rabbit pAb

AO-06-ES4205-50

CD300f rabbit pAb 50μL

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299,00 €
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Antibody Product Overview

ELK.NoES4205
Product nameCD300f rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;IHC;IF;ELISA
Other nameCD300LF; CD300F; CLM1; IGSF13; IREM1; NKIR; CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; Immune receptor expressed on myeloid cells 1; IREM-1; Immunoglobulin superfamily member 13; IgSF13; NK inhibitory receptor; CD300f
Size50μL
Unit price ($)148
Human gene ID146722
Human Swiss-ProtQ8TDQ1
SourceRabbit
IsotypeIgG
TargetCD300f
Fields
Gene nameCD300LF
Protein nameCMRF35-like molecule 1
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID246746
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ6SJQ7
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID287818
Rat gene linkView Rat Gene
Rat Swiss-ProtQ566E6
Rat Swiss linkView Rat Swiss-Prot
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD300LF. AA range:41-90
SpecificityCD300f Polyclonal Antibody detects endogenous levels of CD300f protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)32kD
BackgroundThis gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Functionfunction:Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with PTPN6/SHP-1 in a tyrosine phosphorylation dependent manner.,tissue specificity:Highly expressed in spleen, peripheral blood leukocte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.,
Subcellular locationCell membrane ; Single-pass type I membrane protein .
ExpressionHighly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.

Additional Images

Image 1
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Western Blot analysis of HeLa, PC12 cells using CD300f Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Image 2
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Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
Image 3
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Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
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: AO-06-ES4205-50
: 10 Produits
Hurry! only 10 items left in stock.

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