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Antibody Product Overview
| ELK.No | ES4346 |
| Product name | IL-13Rα2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | IL13RA2; IL13R; Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; Interleukin-13-binding protein; CD213a2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3598 |
| Human Swiss-Prot | Q14627 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IL-13Rα2 |
| Fields | >>Cytokine-cytokine receptor interaction;>>JAK-STAT signaling pathway |
| Gene name | IL13RA2 |
| Protein name | Interleukin-13 receptor subunit alpha-2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O88786 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from Interleukin-13 receptor subunit alpha-2 at AA range: 241-290 |
| Specificity | IL-13Rα2 Polyclonal Antibody detects endogenous levels of IL-13Rα2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 44kD |
| Background | The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008], |
| Function | domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Binds as a monomer with high affinity to interleukin 13 (IL13), but not to IL4.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,similarity:Contains 1 fibronectin type-III domain., |
| Subcellular location | Membrane; Single-pass type I membrane protein. |
| Expression | Brain,Lung,Prostate,Renal cell carcinoma,Testis, |
Additional Images
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Western Blot analysis of HepG2(UV), L929 cells using IL-13Rα2 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western Blot analysis of HEPG2-UV cells using IL-13Rα2 Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
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: AO-06-ES4346-100
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