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Antibody Product Overview
| ELK.No | ES4432 |
| Product name | RCL1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | RCL1; RNAC; RPC2; RPCL1; RTC2; HSPC338; RNA 3'-terminal phosphate cyclase-like protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10171 |
| Human Swiss-Prot | Q9Y2P8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RCL1 |
| Fields | >>Ribosome biogenesis in eukaryotes |
| Gene name | RCL1 |
| Protein name | RNA 3'-terminal phosphate cyclase-like protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 59028 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JJT0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RCL1. AA range:324-373 |
| Specificity | RCL1 Polyclonal Antibody detects endogenous levels of RCL1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | function:Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.,similarity:Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily., |
| Function | function:Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.,similarity:Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily., |
| Subcellular location | Nucleus, nucleolus . |
| Expression | Eye,Seminom,Umbilical cord blood, |
Additional Images
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Western Blot analysis of HUVEC cells using RCL1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western blot analysis of lysates from HUVEC cells, using RCL1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using RCL1 antibody.
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES4432-50
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