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Antibody Product Overview
| ELK.No | ES4473 |
| Product name | Cdx2 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1045 |
| Human Swiss-Prot | Q99626 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CDX2 |
| Fields | >>Gastric cancer |
| Gene name | CDX2 |
| Protein name | Homeobox protein CDX-2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 12591 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P43241 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDX2. AA range:249-298 |
| Specificity | Cdx2 Polyclonal Antibody detects endogenous levels of Cdx2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 45kD |
| Background | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012], |
| Function | function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
| Subcellular location | Nucleus . |
| Expression | Detected in small intestine, colon and pancreas. |
Additional Images
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Western Blot analysis of rat cells using Cdx2 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western blot analysis of lysates from rat heart, using CDX2 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES4473-50
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