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DNAM-1 (phospho Ser329) rabbit pAb
AO-06-ES4531-50
Antibody Product Overview
| ELK.No | ES4531 |
| Product name | DNAM-1 (phospho Ser329) rabbit pAb |
| Reactivity | Human;Mouse;Monkey |
| Applications | WB;IHC;IF;ELISA |
| Other name | CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD antigen CD226 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10666 |
| Human Swiss-Prot | Q15762 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DNAM-1 |
| Fields | >>Cell adhesion molecules |
| Gene name | CD226 |
| Protein name | CD226 antigen |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 225825 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K4F0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD226/DNAM-1 around the phosphorylation site of Ser329. AA range:287-336 |
| Specificity | Phospho-DNAM-1 (S329) Polyclonal Antibody detects endogenous levels of DNAM-1 protein only when phosphorylated at S329. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], |
| Function | function:Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with PVR and PVRL2.,tissue specificity:Expressed by peripheral blood T-lymphocytes., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . |
| Expression | Expressed by peripheral blood T-lymphocytes. |
Additional Images
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Western Blot analysis of COS7 cells using Phospho-DNAM-1 (S329) Polyclonal Antibody
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Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CD226/DNAM-1 (Phospho-Ser329) Antibody
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Immunofluorescence analysis of A549 cells, using CD226/DNAM-1 (Phospho-Ser329) Antibody. The picture on the right is blocked with the phospho peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain, using CD226/DNAM-1 (Phospho-Ser329) Antibody. The picture on the right is blocked with the phospho peptide.
: AO-06-ES4531-50
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