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Antibody Product Overview
| ELK.No | ES4547 |
| Product name | Six2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC |
| Other name | SIX2; Homeobox protein SIX2; Sine oculis homeobox homolog 2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10736 |
| Human Swiss-Prot | Q9NPC8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Six2 |
| Fields | |
| Gene name | SIX2 |
| Protein name | Homeobox protein SIX2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20472 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q62232 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from Six2 . at AA range: 30-110 |
| Specificity | Six2 Polyclonal Antibody detects endogenous levels of Six2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 32kD |
| Observed band (KD) | |
| Background | This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. [provided by RefSeq, Dec 2008], |
| Function | function:May be involved in limb tendon and ligament development.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Strongly expressed in skeletal muscle., |
| Subcellular location | Nucleus . |
| Expression | Strongly expressed in skeletal muscle. Expressed in Wilms' tumor and in the cap mesenchyme of fetal kidney (at protein level). |
Additional Images
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Western blot analysis of SIX2 Antibody. The lane on the right is blocked with the SIX2 peptide.
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Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES4547-100
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