Français
English
Antibody Product Overview
| ELK.No | ES4836 |
| Product name | v-SNARE Vti1a rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | VTI1A; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 143187 |
| Human Swiss-Prot | Q96AJ9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | v-SNARE Vti1a |
| Fields | >>SNARE interactions in vesicular transport |
| Gene name | VTI1A |
| Protein name | Vesicle transport through interaction with t-SNAREs homolog 1A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 53611 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O89116 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 65277 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9JI51 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human VTI1A. AA range:31-80 |
| Specificity | v-SNARE Vti1a Polyclonal Antibody detects endogenous levels of v-SNARE Vti1a protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 23kD |
| Background | The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015], |
| Function | function:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family., |
| Subcellular location | Cytoplasmic vesicle . Golgi apparatus membrane ; Single-pass type IV membrane protein . |
| Expression | Lung, |
Additional Images
No image
Western blot analysis of VTI1A Antibody. The lane on the right is blocked with the VTI1A peptide.
No image
Western blot analysis of the lysates from HUVECcells using VTI1A antibody.
No image
No image
: AO-06-ES4836-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package