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Antibody Product Overview
| ELK.No | ES4878 |
| Product name | ZNF420 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | ZNF420; Zinc finger protein 420 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 147923 |
| Human Swiss-Prot | Q8TAQ5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ZNF420 |
| Fields | >>Herpes simplex virus 1 infection |
| Gene name | ZNF420 |
| Protein name | Zinc finger protein 420 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZNF420. AA range:301-350 |
| Specificity | ZNF420 Polyclonal Antibody detects endogenous levels of ZNF420 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 80kD |
| Background | zinc finger protein 420(ZNF420) Homo sapiens The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016], |
| Function | function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 KRAB domain.,similarity:Contains 19 C2H2-type zinc fingers., |
| Subcellular location | Nucleus . |
| Expression | Muscle,Placenta,Testis, |
Additional Images
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Western Blot analysis of K562 cells using ZNF420 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western blot analysis of ZNF420 Antibody. The lane on the right is blocked with the ZNF420 peptide.
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Western blot analysis of the lysates from COLO205 cells using ZNF420 antibody.
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: AO-06-ES4878-50
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