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Antibody Product Overview
| ELK.No | ES5102 |
| Product name | Net rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | IF;ELISA |
| Other name | ELK3; NET; SAP2; ETS domain-containing protein Elk-3; ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2004 |
| Human Swiss-Prot | P41970 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Net |
| Fields | |
| Gene name | ELK3 |
| Protein name | ETS domain-containing protein Elk-3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13713 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P41971 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Elk3. AA range:323-372 |
| Specificity | Net Polyclonal Antibody detects endogenous levels of Net protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 44kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], |
| Function | function:May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Interacts with CTBP1., |
| Subcellular location | Nucleus. |
| Expression | Brain,Epithelium,Placenta, |
Additional Images
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Immunofluorescence analysis of HeLa cells, using Elk3 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES5102-50
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