| ELK.No | ES5243 |
| Product name | FGF-13 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | FGF13; FHF2; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2258 |
| Human Swiss-Prot | Q92913 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FGF-13 |
| Fields | |
| Gene name | FGF13 |
| Protein name | Fibroblast growth factor 13 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14168 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P70377 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 84488 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9ERW3 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FGF13. AA range:154-203 |
| Specificity | FGF-13 Polyclonal Antibody detects endogenous levels of FGF-13 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 28kD |
| Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008], |
| Function | function:Probably involved in nervous system development and function.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Nervous system., |
| Subcellular location | [Isoform 1]: Nucleus .; [Isoform 2]: Cytoplasm . Nucleus .; [Isoform 3]: Cytoplasm . Nucleus .; [Isoform 4]: Cytoplasm . Nucleus .; [Isoform 5]: Cytoplasm . Nucleus .; Cell projection, filopodium . Cell projection, growth cone . Cell projection, dendrite . Cell membrane, sarcolemma . Cytoplasm . Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. . |
| Expression | Ubiquitously expressed. Predominantly expressed in the nervous system. |


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