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Antibody Product Overview
| ELK.No | ES5274 |
| Product name | Rab 18 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | RAB18; Ras-related protein Rab-18 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 22931 |
| Human Swiss-Prot | Q9NP72 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Rab 18 |
| Fields | |
| Gene name | RAB18 |
| Protein name | Ras-related protein Rab-18 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 19330 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P35293 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 307039 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5EB77 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152 |
| Specificity | Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 28kD |
| Background | The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012], |
| Function | function:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous., |
| Subcellular location | Apical cell membrane . Lipid droplet . |
| Expression | Ubiquitous. |
Additional Images
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Western Blot analysis of MCF-7 cells using Rab 18 Polyclonal Antibody
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Western blot analysis of lysates from MCF-7 and HUVEC cells, using RAB18 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using RAB18 antibody.
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES5274-50
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