Rab 18 rabbit pAb

Rab 18 rabbit pAb

AO-06-ES5274-100

Rab 18 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES5274
Product nameRab 18 rabbit pAb
ReactivityHuman;Mouse;Rat
ApplicationsWB;ELISA;IHC
Other nameRAB18; Ras-related protein Rab-18
Size100μL
Unit price ($)248
Human gene ID22931
Human Swiss-ProtQ9NP72
SourceRabbit
IsotypeIgG
TargetRab 18
Fields
Gene nameRAB18
Protein nameRas-related protein Rab-18
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID19330
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtP35293
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID307039
Rat gene linkView Rat Gene
Rat Swiss-ProtQ5EB77
Rat Swiss linkView Rat Swiss-Prot
ImmunogenThe antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152
SpecificityRab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)28kD
BackgroundThe protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Functionfunction:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
Subcellular locationApical cell membrane . Lipid droplet .
ExpressionUbiquitous.

Additional Images

Image 1
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Western Blot analysis of MCF-7 cells using Rab 18 Polyclonal Antibody
Image 2
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Western blot analysis of lysates from MCF-7 and HUVEC cells, using RAB18 Antibody. The lane on the right is blocked with the synthesized peptide.
Image 3
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Western blot analysis of the lysates from HepG2 cells using RAB18 antibody.
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES5274-100
: 10 Produits
Hurry! only 10 items left in stock.

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