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Antibody Product Overview
| ELK.No | ES5343 |
| Product name | FTβ rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | FNTB; Protein farnesyltransferase subunit beta; FTase-beta; CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2342 |
| Human Swiss-Prot | P49356 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FTβ |
| Fields | >>Terpenoid backbone biosynthesis |
| Gene name | FNTB |
| Protein name | Protein farnesyltransferase subunit beta |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 110606 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K2I1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 64511 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q02293 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304 |
| Specificity | FTβ Polyclonal Antibody detects endogenous levels of FTβ protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 49kD |
| Background | catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit., |
| Function | catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit., |
| Subcellular location | cytosol,microtubule associated complex,protein farnesyltransferase complex, |
| Expression | Neuroblastoma,Placenta,Retina, |
Additional Images
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Western blot analysis of lysates from RAW264.7 abd NIH/3T3 cells, using FNTB Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES5343-50
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