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GATA-2 (phospho Ser401) rabbit pAb
AO-06-ES5477-50
Antibody Product Overview
| ELK.No | ES5477 |
| Product name | GATA-2 (phospho Ser401) rabbit pAb |
| Reactivity | Human;Monkey |
| Applications | WB;ELISA |
| Other name | GATA2; Endothelial transcription factor GATA-2; GATA-binding protein 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2624 |
| Human Swiss-Prot | P23769 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GATA-2 |
| Fields | |
| Gene name | GATA2 |
| Protein name | Endothelial transcription factor GATA-2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O09100 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GATA2 around the phosphorylation site of Ser401. AA range:367-416 |
| Specificity | Phospho-GATA-2 (S401) Polyclonal Antibody detects endogenous levels of GATA-2 protein only when phosphorylated at S401. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 50kD |
| Background | This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009], |
| Function | function:Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.,sequence caution:Several sequencing errors.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Endothelial cells., |
| Subcellular location | Nucleus. |
| Expression | Endothelial cells. |
Additional Images
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Western blot analysis of lysates from COS7 cells treated with TNF 20ng/ml 5', using GATA2 (Phospho-Ser401) Antibody. The lane on the right is blocked with the phospho peptide.
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: AO-06-ES5477-50
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