GATA-6 rabbit pAb

GATA-6 rabbit pAb

AO-06-ES5485-100

GATA-6 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES5485
Product nameGATA-6 rabbit pAb
ReactivityHuman;Mouse;Rat
ApplicationsWB;ELISA
Other nameGATA6; Transcription factor GATA-6; GATA-binding factor 6
Size100μL
Unit price ($)248
Human gene ID2627
Human Swiss-ProtQ92908
SourceRabbit
IsotypeIgG
TargetGATA-6
Fields
Gene nameGATA6
Protein nameTranscription factor GATA-6
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID14465
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ61169
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID29300
Rat gene linkView Rat Gene
Rat Swiss-ProtP46153
Rat Swiss linkView Rat Swiss-Prot
ImmunogenThe antiserum was produced against synthesized peptide derived from human GATA6. AA range:461-510
SpecificityGATA-6 Polyclonal Antibody detects endogenous levels of GATA-6 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)45kD
BackgroundThis gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012],
Functionfunction:Thought to be important for regulating terminal differentiation and/or proliferation.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Expressed in heart, gut and gut-derived tissues.,
Subcellular locationNucleus .
ExpressionExpressed in heart, gut and gut-derived tissues. Expressed in skin upper pilosebaceous unit. Expression is decreased or lost in acne lesions (PubMed:33082341).

Additional Images

Image 1
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Western blot analysis of GATA6 Antibody. The lane on the right is blocked with the GATA6 peptide.
Image 2
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Western blot analysis of the lysates from HepG2 cells using GATA6 antibody.
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: AO-06-ES5485-100
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