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Antibody Product Overview
| ELK.No | ES5528 |
| Product name | Connexin 37 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | GJA4; Gap junction alpha-4 protein; Connexin-37; Cx37 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2701 |
| Human Swiss-Prot | P35212 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Connexin 37 |
| Fields | |
| Gene name | GJA4 |
| Protein name | Gap junction alpha-4 protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14612 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P28235 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25655 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q03190 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GJA4. AA range:81-130 |
| Specificity | Connexin 37 Polyclonal Antibody detects endogenous levels of Connexin 37 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 37kD |
| Background | This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008], |
| Function | function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Expression | Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium. |
Additional Images
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Western blot analysis of lysates from Jurkat cells, using GJA4 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from 293 cells using GJA4 antibody.
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: AO-06-ES5528-100
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