Français
English
Antibody Product Overview
| ELK.No | ES5604 |
| Product name | GPR27 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IF;ELISA |
| Other name | GPR27; SREB1; Probable G-protein coupled receptor 27; Super conserved receptor expressed in brain 1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2850 |
| Human Swiss-Prot | Q9NS67 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GPR27 |
| Fields | |
| Gene name | GPR27 |
| Protein name | Probable G-protein coupled receptor 27 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14761 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O54897 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 65275 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9JJH3 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GPR27. AA range:181-230 |
| Specificity | GPR27 Polyclonal Antibody detects endogenous levels of GPR27 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 39kD |
| Background | GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010], |
| Function | function:Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum. |
Additional Images
No image
Immunofluorescence analysis of A549 cells, using GPR27 Antibody. The picture on the right is blocked with the synthesized peptide.
No image
Western blot analysis of lysates from HUVEC cells, using GPR27 Antibody. The lane on the right is blocked with the synthesized peptide.
No image
Western blot analysis of the lysates from HeLa cells using GPR27 antibody.
No image
: AO-06-ES5604-50
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package