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Antibody Product Overview
| ELK.No | ES5620 |
| Product name | GPR43 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | IF;ELISA |
| Other name | FFAR2; GPR43; Free fatty acid receptor 2; G-protein coupled receptor 43 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2867 |
| Human Swiss-Prot | O15552 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GPR43 |
| Fields | >>cAMP signaling pathway |
| Gene name | FFAR2 |
| Protein name | Free fatty acid receptor 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8VCK6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FFAR2. AA range:271-320 |
| Specificity | GPR43 Polyclonal Antibody detects endogenous levels of GPR43 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 37kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009], |
| Function | function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Expressed at relatively high levels in peripheral blood leukocytes and, to lesser extent, in spleen. |
Additional Images
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Immunofluorescence analysis of COS7 cells, using FFAR2 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES5620-100
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