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Antibody Product Overview
| ELK.No | ES6104 |
| Product name | Galectin-1 rabbit pAb |
| Reactivity | Human;Rat;Deer |
| Applications | WB;ELISA |
| Other name | LGALS1; Galectin-1; Gal-1; 14 kDa laminin-binding protein; HLBP14; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; HBL; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; Putative MAPK-activating protein P |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3956 |
| Human Swiss-Prot | P09382 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Galectin-1 |
| Fields | |
| Gene name | LGALS1 |
| Protein name | Galectin-1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P16045 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 56646 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P11762 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from Galectin-1 . at AA range: 10-90 |
| Specificity | Galectin-1 Polyclonal Antibody detects endogenous levels of Galectin-1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 15kD |
| Background | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008], |
| Function | function:May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.,online information:Galectin-1,similarity:Contains 1 galectin domain.,subunit:Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45.,tissue specificity:Cardiac, smooth, and skeletal muscle, neurons, thymus, kidney, placenta and hematopoietic cells., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . Cytoplasm . Secreted . Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. . |
| Expression | Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. |
Additional Images
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Western Blot analysis of 3T3 cells using Galectin-1 Polyclonal Antibody diluted at 1:500
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: AO-06-ES6104-100
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