Français
English
Antibody Product Overview
| ELK.No | ES6216 |
| Product name | Malic enzyme 1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | ME1; NADP-dependent malic enzyme; NADP-ME; Malic enzyme 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4199 |
| Human Swiss-Prot | P48163 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Malic enzyme 1 |
| Fields | >>Pyruvate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>PPAR signaling pathway |
| Gene name | ME1 |
| Protein name | NADP-dependent malic enzyme |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 17436 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P06801 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P13697 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ME1. AA range:468-517 |
| Specificity | Malic enzyme 1 Polyclonal Antibody detects endogenous levels of Malic enzyme 1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 64kD |
| Background | This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the malic enzymes family.,subunit:Homotetramer.,tissue specificity:Expressed in all tissues tested including liver, placenta and white adipose tissue., |
| Subcellular location | Cytoplasm . |
| Expression | Expressed in all tissues tested including liver, placenta and white adipose tissue. |
Additional Images
No image
Western blot analysis of lysates from HeLa cells, using ME1 Antibody. The lane on the right is blocked with the synthesized peptide.
No image
Western blot analysis of the lysates from HeLa cells using ME1 antibody.
No image
No image
: AO-06-ES6216-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package