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Antibody Product Overview
| ELK.No | ES6282 |
| Product name | AKAP 2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | AKAP2; KIAA0920; PRKA2; A-kinase anchor protein 2; AKAP-2; AKAP-KL; Protein kinase A-anchoring protein 2; PRKA2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 445815/11217 |
| Human Swiss-Prot | Q9Y2D5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AKAP 2 |
| Fields | |
| Gene name | AKAP2 |
| Protein name | A-kinase anchor protein 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O54931 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AKAP2. AA range:71-120 |
| Specificity | AKAP 2 Polyclonal Antibody detects endogenous levels of AKAP 2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 96kD |
| Background | The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011], |
| Function | caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP.,miscellaneous:Can be differentially expressed as a natural AKAP2-PALM2 chimeric protein.,similarity:Belongs to the paralemmin family.,tissue specificity:Expressed in infantile heart and muscle, and fibroblasts., |
| Subcellular location | |
| Expression | Brain,Epithelium,Hippocampus,Liver,Muscle,Small intestine,Trachea, |
Additional Images
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Western blot analysis of lysates from LOVO cells, using AKAP2 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES6282-100
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