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Antibody Product Overview
| ELK.No | ES6300 |
| Product name | A-Myb rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | MYBL1; AMYB; Myb-related protein A; A-Myb; Myb-like protein 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4603 |
| Human Swiss-Prot | P10243 |
| Source | Rabbit |
| Isotype | IgG |
| Target | A-Myb |
| Fields | |
| Gene name | MYBL1 |
| Protein name | Myb-related protein A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 17864 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P51960 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280 |
| Specificity | A-Myb Polyclonal Antibody detects endogenous levels of A-Myb protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | function:Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro., |
| Function | function:Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro., |
| Subcellular location | Nucleus . |
| Expression | Expressed in a variety of lymphoid and solid tumor lines cultured in vitro. |
Additional Images
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Western blot analysis of lysates from LOVO cells, using MYB-A Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES6300-100
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