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Ribosomal Protein L10A rabbit pAb
AO-06-ES6355-50
Antibody Product Overview
| ELK.No | ES6355 |
| Product name | Ribosomal Protein L10A rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | RPL10A; NEDD6; 60S ribosomal protein L10a; CSA-19; Neural precursor cell expressed developmentally down-regulated protein 6; NEDD-6 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4736 |
| Human Swiss-Prot | P62906 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Ribosomal Protein L10A |
| Fields | >>Ribosome;>>Coronavirus disease - COVID-19 |
| Gene name | RPL10A |
| Protein name | 60S ribosomal protein L10a |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P53026 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 81729 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P62907 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from Ribosomal Protein L10A . at AA range: 30-110 |
| Specificity | Ribosomal Protein L10A Polyclonal Antibody detects endogenous levels of Ribosomal Protein L10A protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes |
| Function | similarity:Belongs to the ribosomal protein L1P family., |
| Subcellular location | nucleus,nucleolus,cytoplasm,cytosol,ribosome,focal adhesion,large ribosomal subunit,membrane,cytosolic large ribosomal subunit,extracellular exosome, |
| Expression | Breast,Cervix, |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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