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DOR-1 (phospho Ser363) rabbit pAb
AO-06-ES6441-50
Antibody Product Overview
| ELK.No | ES6441 |
| Product name | DOR-1 (phospho Ser363) rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | OPRD1; OPRD; Delta-type opioid receptor; D-OR-1; DOR-1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4985 |
| Human Swiss-Prot | P41143 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DOR-1 |
| Fields | >>cGMP-PKG signaling pathway;>>Sphingolipid signaling pathway;>>Neuroactive ligand-receptor interaction |
| Gene name | OPRD1 |
| Protein name | Delta-type opioid receptor |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18386 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P32300 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 24613 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P33533 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Opioid Receptor-delta around the phosphorylation site of Ser363. AA range:323-372 |
| Specificity | Phospho-DOR-1 (S363) Polyclonal Antibody detects endogenous levels of DOR-1 protein only when phosphorylated at S363. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 36kD |
| Background | function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.,online information:Delta opioid receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with GPRASP1., |
| Function | function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.,online information:Delta opioid receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with GPRASP1., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. |
Additional Images
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Western Blot analysis of 293 cells using Phospho-DOR-1 (S363) Polyclonal Antibody
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Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Opioid Receptor-delta (Phospho-Ser363) Antibody
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Immunohistochemistry analysis of paraffin-embedded human brain, using Opioid Receptor-delta (Phospho-Ser363) Antibody. The picture on the right is blocked with the phospho peptide.
: AO-06-ES6441-50
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