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Antibody Product Overview
| ELK.No | ES6559 |
| Product name | Endomucin rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | IF;ELISA |
| Other name | EMCN; EMCN2; MUC14; Endomucin; Endomucin-2; Gastric cancer antigen Ga34; Mucin-14; MUC-14 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 51705 |
| Human Swiss-Prot | Q9ULC0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Endomucin |
| Fields | |
| Gene name | EMCN |
| Protein name | Endomucin |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 59308 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9R0H2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 295490 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6AY82 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Mucin-14. AA range:201-250 |
| Specificity | Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 27kD |
| Observed band (KD) | |
| Background | endomucin(EMCN) Homo sapiens EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008], |
| Function | function:Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.,PTM:Highly O-glycosylated. Sialic acid-rich glycoprotein.,subcellular location:Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.,tissue specificity:Expressed in heart, kidney and lung., |
| Subcellular location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.; [Isoform 2]: Secreted . |
| Expression | Expressed in heart, kidney and lung. |
Additional Images
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Immunofluorescence analysis of HepG2 cells, using Mucin-14 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES6559-100
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