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Antibody Product Overview
| ELK.No | ES6663 |
| Product name | Brn-3a rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | POU4F1; BRN3A; RDC1; POU domain; class 4, transcription factor 1; Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5457 |
| Human Swiss-Prot | Q01851 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Brn-3a |
| Fields | |
| Gene name | POU4F1 |
| Protein name | POU domain class 4 transcription factor 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18996 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P17208 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P20266 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human POU4F1. AA range:311-360 |
| Specificity | Brn-3a Polyclonal Antibody detects endogenous levels of Brn-3a protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 42kD |
| Background | This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012], |
| Function | developmental stage:Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth.,function:Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.,similarity:Belongs to the POU transcription factor family. Class-4 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye., |
| Subcellular location | Nucleus . Cytoplasm . |
| Expression | Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye. |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES6663-50
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