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Antibody Product Overview
| ELK.No | ES6681 |
| Product name | CDKAL1 rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB;ELISA |
| Other name | CDKAL1; Threonylcarbamoyladenosine tRNA methylthiotransferase; CDK5 regulatory subunit-associated protein 1-like 1; tRNA-t(6)A37 methylthiotransferase |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 54901 |
| Human Swiss-Prot | Q5VV42 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CDKAL1 |
| Fields | |
| Gene name | CDKAL1 |
| Protein name | Threonylcarbamoyladenosine tRNA methylthiotransferase |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q91WE6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDKAL. AA range:10-59 |
| Specificity | CDKAL1 Polyclonal Antibody detects endogenous levels of CDKAL1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 65kD |
| Background | The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010], |
| Function | cofactor:Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.,similarity:Belongs to the methylthiotransferase family. CDKAL1 subfamily.,similarity:Contains 1 MTTase N-terminal domain.,similarity:Contains 1 TRAM domain., |
| Subcellular location | Endoplasmic reticulum membrane ; Single-pass membrane protein . Is a tail-anchored protein that exploits the TCR40 pathway for insertion into the endoplasmic reticulum. . |
| Expression | Expressed in pancreatic islets. |
Additional Images
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Western Blot analysis of CoLo cells using CDKAL1 Polyclonal Antibody
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: AO-06-ES6681-50
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