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Antibody Product Overview
| ELK.No | ES6928 |
| Product name | BAI-3 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | IHC;IF;ELISA |
| Other name | BAI3; KIAA0550; Brain-specific angiogenesis inhibitor 3 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 577 |
| Human Swiss-Prot | O60242 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BAI-3 |
| Fields | |
| Gene name | BAI3 |
| Protein name | Brain-specific angiogenesis inhibitor 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 210933 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80ZF8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BAI3. AA range:211-260 |
| Specificity | BAI-3 Polyclonal Antibody detects endogenous levels of BAI-3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 171kD |
| Observed band (KD) | |
| Background | This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008], |
| Function | function:Might be involved in angiogenesis inhibition and suppression of glioblastoma.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,tissue specificity:Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines. |
Additional Images
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Immunofluorescence analysis of HUVEC cells, using BAI3 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using BAI3 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES6928-100
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