Français
English
Antibody Product Overview
| ELK.No | ES6990 |
| Product name | Rap 2B rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC |
| Other name | RAP2B; Ras-related protein Rap-2b |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5912 |
| Human Swiss-Prot | P61225 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Rap 2B |
| Fields | |
| Gene name | RAP2B |
| Protein name | Ras-related protein Rap-2b |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 74012 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P61226 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 170923 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P61227 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAP2B. AA range:98-147 |
| Specificity | Rap 2B Polyclonal Antibody detects endogenous levels of Rap 2B protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 18kD |
| Background | This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008], |
| Function | domain:The effector domain mediates the interaction with RUNDC3A.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A., |
| Subcellular location | Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Associated with red blood cells-released vesicles. |
| Expression | Expressed in red blood cells (at protein level). |
Additional Images
No image
Western blot analysis of the lysates from COLO205 cells using RAP2B antibody.
No image
Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
No image
No image
: AO-06-ES6990-50
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package