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Antibody Product Overview
| ELK.No | ES7056 |
| Product name | Tip5 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC |
| Other name | BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 605682 |
| Human Swiss-Prot | Q9UIF9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Tip5 |
| Fields | |
| Gene name | BAZ2A |
| Protein name | Bromodomain adjacent to zinc finger domain protein 2A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q91YE5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BAZ2A. AA range:1281-1330 |
| Specificity | Tip5 Polyclonal Antibody detects endogenous levels of Tip5 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 210kD |
| Background | function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas., |
| Function | function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 MBD (methyl-CpG-binding) domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 4 A.T hook DNA-binding domains.,subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus.,subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex).,tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney |
| Subcellular location | Nucleus, nucleolus . Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. . |
| Expression | Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. |
Additional Images
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Western blot analysis of the lysates from HeLa cells using BAZ2A antibody.
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES7056-100
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