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Antibody Product Overview
| ELK.No | ES7170 |
| Product name | Cadherin-22 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | CDH22; C20orf25; Cadherin-22; Pituitary and brain cadherin; PB-cadherin |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 64405 |
| Human Swiss-Prot | Q9UJ99 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Cadherin-22 |
| Fields | |
| Gene name | CDH22 |
| Protein name | Cadherin-22 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WTP5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29182 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63315 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDH22. AA range:111-160 |
| Specificity | Cadherin-22 Polyclonal Antibody detects endogenous levels of Cadherin-22 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 84kD |
| Background | This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008], |
| Function | function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.,similarity:Contains 5 cadherin domains., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . |
| Expression | Brain,Testis, |
Additional Images
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Immunofluorescence analysis of NIH/3T3 cells, using CDH22 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH22 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from rat brain cells, using CDH22 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES7170-50
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