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Antibody Product Overview
| ELK.No | ES7239 |
| Product name | PHACTR4 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA;IHC |
| Other name | PHACTR4; Phosphatase and actin regulator 4 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 65979 |
| Human Swiss-Prot | Q8IZ21 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PHACTR4 |
| Fields | |
| Gene name | PHACTR4 |
| Protein name | Phosphatase and actin regulator 4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q501J7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PHACTR4. AA range:363-412 |
| Specificity | PHACTR4 Polyclonal Antibody detects endogenous levels of PHACTR4 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 80kD |
| Background | This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Function | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase and actin regulator family.,similarity:Contains 3 RPEL repeats.,subunit:Binds PPP1CA and actin., |
| Subcellular location | Cytoplasm . Cell projection, lamellipodium . |
| Expression | Adrenal cortex,Fetal brain,Fetal liver,Skin,Testis, |
Additional Images
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Western blot analysis of PHACTR4 Antibody. The lane on the right is blocked with the PHACTR4 peptide.
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Western blot analysis of the lysates from HeLa cells using PHACTR4 antibody.
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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES7239-50
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