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Antibody Product Overview
| ELK.No | ES7446 |
| Product name | TRH-R1 rabbit pAb |
| Reactivity | Human;Mouse;Rat;Monkey |
| Applications | WB;IF;ELISA |
| Other name | TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 7201 |
| Human Swiss-Prot | P34981 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TRH-R1 |
| Fields | >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction |
| Gene name | TRHR |
| Protein name | Thyrotropin-releasing hormone receptor |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 22045 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P21761 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25570 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q01717 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TRHR. AA range:195-244 |
| Specificity | TRH-R1 Polyclonal Antibody detects endogenous levels of TRH-R1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 50kD |
| Background | This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011], |
| Function | function:Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Brain,Pituitary,Placenta, |
Additional Images
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Immunofluorescence analysis of A549 cells, using TRHR Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from COS7 cells, using TRHR Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using TRHR antibody.
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: AO-06-ES7446-100
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