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Antibody Product Overview
| ELK.No | ES7591 |
| Product name | LRRK1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | IHC;IF;ELISA |
| Other name | LRRK1; KIAA1790; Leucine-rich repeat serine/threonine-protein kinase 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 79705 |
| Human Swiss-Prot | Q38SD2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LRRK1 |
| Fields | |
| Gene name | LRRK1 |
| Protein name | Leucine-rich repeat serine/threonine-protein kinase 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q3UHC2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LRRK1. AA range:361-410 |
| Specificity | LRRK1 Polyclonal Antibody detects endogenous levels of LRRK1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 228kD |
| Observed band (KD) | |
| Background | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats., |
| Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats., |
| Subcellular location | Cytoplasm . |
| Expression | Brain,Cervix,Lung,Macrophage,Pancreas,Skin,Spleen, |
Additional Images
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Immunofluorescence analysis of HeLa cells, using LRRK1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LRRK1 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES7591-100
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