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Antibody Product Overview
| ELK.No | ES7788 |
| Product name | Rab 2B rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB; ELISA;IHC |
| Other name | RAB2B; Ras-related protein Rab-2B |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 84932 |
| Human Swiss-Prot | Q8WUD1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Rab 2B |
| Fields | |
| Gene name | RAB2B |
| Protein name | Ras-related protein Rab-2B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 76338 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P59279 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAB2B. AA range:103-152 |
| Specificity | Rab 2B Polyclonal Antibody detects endogenous levels of Rab 2B protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 24kD |
| Background | Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006], |
| Function | function:Required for protein transport from the endoplasmic reticulum to the Golgi complex .,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte., |
| Subcellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endoplasmic reticulum membrane ; Lipid-anchor . Golgi apparatus membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid. . |
| Expression | Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte. |
Additional Images
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Western blot analysis of RAB2B Antibody. The lane on the right is blocked with the RAB2B peptide.
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Western blot analysis of the lysates from 293 cells using RAB2B antibody.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES7788-50
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