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Antibody Product Overview
| ELK.No | ES7814 |
| Product name | PRIC285 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA;IHC |
| Other name | PRIC285; KIAA1769; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein; ATP-dependent helicase PRIC285; PPAR-alpha-interacting complex protein 285; PPAR-gamma DNA-binding domain-interacting protein 1; PDIP1; PP |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 85441 |
| Human Swiss-Prot | Q9BYK8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PRIC285 |
| Fields | |
| Gene name | PRIC285 |
| Protein name | Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PRIC285. AA range:1909-1958 |
| Specificity | PRIC285 Polyclonal Antibody detects endogenous levels of PRIC285 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 300kD |
| Background | The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Function | caution:PubMed:12189208 experiments have been carried out partly in rat and partly in human.,domain:Contains 5 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs. These motifs are not required for interaction with PPARG.,function:Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA.,similarity:Belongs to the DNA2/NAM7 helicase family.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Interacts with PPARA, ESR1, THRB and RXRA. It is probably part of the peroxisome proliferator activated receptor alpha interacting complex (PRIC). Also interacts with the DNA-binding domain of PPARG.,tissue specificity:Expressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta., |
| Subcellular location | Nucleus . |
| Expression | Expressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta. |
Additional Images
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Western blot analysis of PRIC285 Antibody. The lane on the right is blocked with the PRIC285 peptide.
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Western blot analysis of the lysates from HT-29 cells using PRIC285 antibody.
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES7814-100
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