Megsin rabbit pAb

Megsin rabbit pAb

AO-06-ES7864-50

Megsin rabbit pAb 50μL

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299,00 €
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Antibody Product Overview

ELK.NoES7864
Product nameMegsin rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;ELISA
Other nameSERPINB7; Serpin B7; Megsin; TP55
Size50μL
Unit price ($)148
Human gene ID8710
Human Swiss-ProtO75635
SourceRabbit
IsotypeIgG
TargetMegsin
Fields
Gene nameSERPINB7
Protein nameSerpin B7
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ9D695
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenThe antiserum was produced against synthesized peptide derived from human SERPINB7. AA range:111-160
SpecificityMegsin Polyclonal Antibody detects endogenous levels of Megsin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)43kD
BackgroundThis gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
Functionfunction:Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Predominantly expressed in mesangial cells.,
Subcellular locationCytoplasm .
ExpressionPredominantly expressed in mesangial cells. Expressed in the epidermis of the whole body.

Additional Images

Image 1
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Western blot analysis of lysates from Jurkat cells, using SERPINB7 Antibody. The lane on the right is blocked with the synthesized peptide.
Image 2
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Western blot analysis of the lysates from Jurkat cells using SERPINB7 antibody.
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: AO-06-ES7864-50
: 10 Produits
Hurry! only 10 items left in stock.

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