| ELK.No | ES7879 |
| Product name | Dyrk4 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | DYRK4; Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8798 |
| Human Swiss-Prot | Q9NR20 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Dyrk4 |
| Fields | |
| Gene name | DYRK4 |
| Protein name | Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BI55 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from Dyrk4 . at AA range: 350-430 |
| Specificity | Dyrk4 Polyclonal Antibody detects endogenous levels of Dyrk4 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013], |
| Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Possible non-essential role in spermiogenesis.,PTM:Autophosphorylated on tyrosine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain., |
| Subcellular location | [Isoform 1]: Cytoplasm .; [Isoform 4]: Cytoplasm . Nucleus . |
| Expression | Brain,Kidney,Lung,Testis, |

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