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Antibody Product Overview
| ELK.No | ES8022 |
| Product name | TFIIIC90 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | GTF3C4; General transcription factor 3C polypeptide 4; TF3C-delta; Transcription factor IIIC 90 kDa subunit; TFIIIC 90 kDa subunit; TFIIIC90; Transcription factor IIIC subunit delta |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9329 |
| Human Swiss-Prot | Q9UKN8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TFIIIC90 |
| Fields | |
| Gene name | GTF3C4 |
| Protein name | General transcription factor 3C polypeptide 4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BMQ2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TF3C4. AA range:611-660 |
| Specificity | TFIIIC90 Polyclonal Antibody detects endogenous levels of TFIIIC90 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 95kD |
| Background | catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the TFIIIC subunit 4 family.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F., |
| Function | catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the TFIIIC subunit 4 family.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F., |
| Subcellular location | Nucleus. |
| Expression | Brain,Epithelium,Placenta,Testis, |
Additional Images
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Western blot analysis of TF3C4 Antibody. The lane on the right is blocked with the TF3C4 peptide.
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Western blot analysis of the lysates from HUVECcells using TF3C4 antibody.
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: AO-06-ES8022-100
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