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Antibody Product Overview
| ELK.No | ES8078 |
| Product name | Gα 14 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | GNA14; Guanine nucleotide-binding protein subunit alpha-14; G alpha-14; G-protein subunit alpha-14 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9630 |
| Human Swiss-Prot | O95837 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Gα 14 |
| Fields | >>Calcium signaling pathway;>>Chagas disease;>>Amoebiasis |
| Gene name | GNA14 |
| Protein name | Guanine nucleotide-binding protein subunit alpha-14 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14675 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P30677 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GNA14. AA range:1-50 |
| Specificity | Gα 14 Polyclonal Antibody detects endogenous levels of Gα 14 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 42kD |
| Background | This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009], |
| Function | function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(q) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site., |
| Subcellular location | heterotrimeric G-protein complex,plasma membrane,extracellular exosome, |
| Expression | Caudate nucleus,Pancreas,Spleen, |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES8078-100
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