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Antibody Product Overview
| ELK.No | ES8424 |
| Product name | CMTM8 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | CMTM8; CKLFSF8; CKLF-like MARVEL transmembrane domain-containing protein 8; Chemokine-like factor superfamily member 8 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 152189 |
| Human Swiss-Prot | Q8IZV2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CMTM8 |
| Fields | |
| Gene name | CMTM8 |
| Protein name | CKLF-like MARVEL transmembrane domain-containing protein 8 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 70031 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CZR4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CMTM8. AA range:101-150 |
| Specificity | CMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 20kD |
| Background | This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016], |
| Function | similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in liver and pancreas., |
| Subcellular location | [Isoform 1]: Membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm. Nucleus. |
| Expression | Highly expressed in liver and pancreas. |
Additional Images
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Western blot analysis of hela lysis using CMTM8 antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:200
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Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:200
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Immunohistochemical analysis of paraffin-embedded human-tonsils2, antibody was diluted at 1:100
: AO-06-ES8424-50
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