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Antibody Product Overview
| ELK.No | ES8527 |
| Product name | ULK2 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | ULK2 KIAA0623 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9706 |
| Human Swiss-Prot | Q8IYT8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ULK2 |
| Fields | >>Autophagy - other;>>Autophagy - animal;>>mTOR signaling pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases |
| Gene name | ULK2 KIAA0623 |
| Protein name | unc-51-like kinase 2 (C. elegans) |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 29869 |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9QY01 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic peptide from human protein at AA range: 930-1000 |
| Specificity | The antibody detects endogenous ULK2 protein |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 140kD |
| Background | unc-51 like autophagy activating kinase 2(ULK2) Homo sapiens This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008], |
| Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain., |
| Subcellular location | Cytoplasmic vesicle membrane ; Peripheral membrane protein . Localizes to pre-autophagosomal membrane. |
| Expression | Brain,Testis, |
Additional Images
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Western Blot analysis of HELA cells using Antibody diluted at 500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES8527-50
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