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Antibody Product Overview
| ELK.No | ES8546 |
| Product name | FAM48A rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | FAM48A C13orf19 FP757 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 55578 |
| Human Swiss-Prot | Q8NEM7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FAM48A |
| Fields | >>Autophagy - animal |
| Gene name | FAM48A C13orf19 FP757 |
| Protein name | family with sequence similarity 48, member A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56790 |
| Mouse gene link | |
| Mouse Swiss-Prot | Q7TT00 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q66HC7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280 |
| Specificity | The antibody detects endogenous FAM48A protein |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.,similarity:Belongs to the FAM48 family.,subunit:Interacts with MAPK14.,tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues., |
| Function | function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.,similarity:Belongs to the FAM48 family.,subunit:Interacts with MAPK14.,tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues., |
| Subcellular location | Nucleus . |
| Expression | Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues. |
Additional Images
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Western Blot analysis of mouse-kidney cells using Antibody diluted at 1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES8546-100
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