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ACSS1 (Acetyl-K642) rabbit pAb
AO-06-ES8818-50
Antibody Product Overview
| ELK.No | ES8818 |
| Product name | ACSS1 (Acetyl-K642) rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 84532 |
| Human Swiss-Prot | Q9NUB1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ACSS1 |
| Fields | >>Glycolysis / Gluconeogenesis;>>Pyruvate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Propanoate metabolism;>>Metabolic pathways;>>Carbon metabolism |
| Gene name | ACSS1 ACAS2L KIAA1846 |
| Protein name | ACSS1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q99NB1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized Acetyl peptide derived from human ACSS1. at AA range: K642 |
| Specificity | This antibody detects endogenous levels of ACSS1 at Human:K642;Mouse:K635;Rat:K635, It doesn't reacte with total protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | |
| Background | This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011], |
| Function | catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).,sequence caution:Sequencing errors.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family., |
| Subcellular location | Mitochondrion matrix . |
| Expression | Amygdala,Brain,PCR rescued clones,Placenta,Spleen,Stomach,T |
Additional Images
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Western Blot analysis of 1,293T 2,hela cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
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: AO-06-ES8818-50
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