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Antibody Product Overview
| ELK.No | ES8865 |
| Product name | AVPR1A rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 552 |
| Human Swiss-Prot | P37288 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AVPR1A |
| Fields | >>Calcium signaling pathway;>>Phospholipase D signaling pathway;>>Neuroactive ligand-receptor interaction;>>Vascular smooth muscle contraction |
| Gene name | AVPR1A |
| Protein name | AVPR1A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 54140 |
| Mouse gene link | |
| Mouse Swiss-Prot | Q62463 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human AVPR1A. at AA range: 11-60 |
| Specificity | AVPR1A Polyclonal Antibody detects endogenous levels of AVPR1A |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008], |
| Function | function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.,miscellaneous:Differences in regional receptor expression in the brain as well as differences in social behavior may result from a highly variable repetitive sequence in the 5' flanking region of AVPR1A. One such allelic variant has been linked to autism.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | Liver,Lung, |
Additional Images
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Western Blot analysis of mouse-lung cells using primary antibody diluted at 1:500(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
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: AO-06-ES8865-50
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