Français
English
eEF2 (Phospho-Thr56) Rabbit pAb
AO-06-ES8874-100
Antibody Product Overview
| ELK.No | ES8874 |
| Product name | eEF2 (Phospho-Thr56) Rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | Elongation factor 2 (EF-2) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 1938 |
| Human Swiss-Prot | P13639 |
| Source | Rabbit |
| Isotype | IgG |
| Target | eEF2 |
| Fields | >>AMPK signaling pathway;>>Oxytocin signaling pathway |
| Gene name | EEF2 EF2 |
| Protein name | Elongation factor 2 (EF-2) |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13629 |
| Mouse gene link | |
| Mouse Swiss-Prot | P58252 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29565 |
| Rat gene link | |
| Rat Swiss-Prot | P05197 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized phospho derived from human eEF2 (Phospho-Thr56) |
| Specificity | This detects endogenous levels of eEF2 (Phospho-Thr56) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 100kD |
| Background | This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008], |
| Function | function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9., |
| Subcellular location | Cytoplasm . Nucleus . Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. . |
| Expression | Brain,Cajal-Retzius cell,Epithelium,Hepatocyte,Ovary,Periph |
Additional Images
No image
Western blot analysis of various lysate, antibody was diluted at 1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
No image
No image
No image
: AO-06-ES8874-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package