FSBP rabbit pAb

FSBP rabbit pAb

AO-06-ES9031-100

FSBP rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES9031
Product nameFSBP rabbit pAb
ReactivityHuman;Mouse
ApplicationsWB;ELISA
Other name
Size100μL
Unit price ($)248
Human gene ID100861412
Human Swiss-ProtO95073
SourceRabbit
IsotypeIgG
TargetFSBP
Fields
Gene nameFSBP
Protein nameFibrinogen silencer-binding protein
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ8BKE5
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-ProtD3ZXW3
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human protein . at AA range: 110-190
SpecificityFSBP Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)32kD
Backgrounddisease:Defects in RAD54B may be a cause of tumor formation. Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer. These findings suggest that some cancers arise through defects of the RAD54B function.,function:Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect.,tissue specificity:Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.,
Functiondisease:Defects in RAD54B may be a cause of tumor formation. Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer. These findings suggest that some cancers arise through defects of the RAD54B function.,function:Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect.,tissue specificity:Abundantly expressed in testis and spleen. Relatively low levels observed in thymu
Subcellular locationNucleus .
ExpressionExpressed in multiple tissues including brain.

Additional Images

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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9031-100
: 10 Produits
Hurry! only 10 items left in stock.

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