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Antibody Product Overview
| ELK.No | ES9183 |
| Product name | ITBP2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26548 |
| Human Swiss-Prot | Q9UKP3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ITBP2 |
| Fields | |
| Gene name | ITGB1BP2 MSTP015 |
| Protein name | Integrin beta-1-binding protein 2 (Melusin) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9R000 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Specificity | ITBP2 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | domain:The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.,function:May play a role during maturation and/or organization of muscles cells.,similarity:Contains 1 CS domain.,similarity:Contains 2 CHORD domains.,subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.,tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues., |
| Function | domain:The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.,function:May play a role during maturation and/or organization of muscles cells.,similarity:Contains 1 CS domain.,similarity:Contains 2 CHORD domains.,subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.,tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues., |
| Subcellular location | Z disc, |
| Expression | Expressed in skeletal and cardiac muscles but not in other tissues. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9183-100
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